The first Whitley A145 HEPA Workstation installation: FLI in Germany

Meintrup DWS technicians Adnan Husanovic and Stefan Fritz installed the first Whitley A145 HEPA Workstation at the Leibniz Institute for Age Research - Fritz Lipmann Institute (FLI), Jena, Germany, on 6 June 2024. The training on the A145 HEPA and user instruction was conducted by sales representative Sandra Lasota. This workstation is part of the research group led by Dr Correia-Melo, specialising in the areas of microbiome and metabolism.

The Correia-Melo research group at FLI focuses on investigating the interactions between the microbiome and metabolism. Cells not only take up nutrients from their environment but also release various metabolic products crucial for the metabolic balance within the cell. The release of these metabolites influences the physiological processes of the cells and can have implications for health, diseases, and therapies.

The group studies the metabolic microenvironments that arise from the exchange of metabolites between cells, both during healthy and disease-related aging processes. They address questions about the effects of these metabolites on the physiology of neighboring cells, the aging process, diseases, the interaction between host cells and the microbiome, and the impact of medical therapies. To answer these questions, the lab employs state-of-the-art analytical methods, including high-throughput mass spectrometry analysis techniques such as metabolomics and proteomics. By combining molecular biology low-throughput methods with mammalian and microbial model systems, the research group aims to achieve a mechanistic understanding of metabolic microenvironments at a systems level.

The main research areas include the metabolic interactions between host and microbiome during aging, the metabolic microenvironment as a driving force in the onset and progression of diseases, and the role of therapy-induced cell senescence microenvironments in the persistence of diseases.

Discoveries at these levels have the potential to be translated into innovative therapies targeting metabolism and contributing to the maintenance of health. The installation of the Whitley A145 HEPA Workstation at FLI will help the group efficiently and accurately pursue their research goals.

Meintrup DWS is proud to be involved with such a prestigious organisation and wish them well in future research endeavours.

If you require any further information about the range of anaerobic or HEPA workstations, please contact our sales team: sales@dwscientific.co.uk