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Sally Oswald, a postdoctoral research associate from Prof Claire Eyers’ research group at the University of Liverpool, recently used the Don Whitley Scientific Travel Grant to attend the ASMS (American Society of Mass Spectrometry) Conference in Anaheim, California.
This is Sally’s second time using one of our travel grants, with the first being in December 2022 where she attended the HUPO (Human Proteome Organization) Conference in Cancun, Mexico as a PhD student. This time Sally presented her research focusing on the role of protein zDHHC23 and its palmitoyltransferase activity in normoxic and hypoxic conditions.
Sally has shown that the protein interactors and palmitoylated mediated targets (identified using copper-based click-chemistry) of zDHHC23 and their subsequent signalling pathways differ substantially depending on normoxic or hypoxic incubation of neuroblastoma cells. Hypoxia was used to mimic an aggressive metastatic cell phenotype allowing the identification of key proteins and pathways that has helped to elucidate the role of zDHHC23 (expanding current literature only showing one known protein interactor) and why its upregulation in neuroblastoma patients results in an abysmal prognosis. For her work, Sally used a Whitley H35 Hypoxystation at the Eyers lab, in Liverpool.
We are pleased to see our workstations helping to facilitate postdoctoral research and we congratulate Sally on receiving the Don Whitley Scientific Travel Grant and presenting in California. If you are interested in our travel grants, please find more details on the Travel Grant page. For more information on our Hypoxystation range please see the products below or email us at sales@dwscientific.co.uk.
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